From the Wikipedia page 
Kyankwanzi District is the northernmost district in the Central Region of Uganda and Buganda Kingdom, bordering Bunyoro. The district headquarters are in Butemba Town.
The Kyankwanzi District borders with the Nakaseke District to the east across the Mayanja River, Kiboga District to the south-east, Mubende and Kibaale Districts to the south-west across the Lugogo River, and Hoima and Masindi Districts to the north across the River Kafu. The district headquarters in Butemba Town on the Bukwiri-Kyankwanzi Road are approximately 160 km by road from Kampala, the nation's capital.